Dr. Daniel Perl was born and raised in New York City and received his undergraduate degree from Columbia and his medical training at the State University of New York, Downstate Medical Center. He then took postgraduate training in anatomic pathology and neuropathology at Yale University, following which he served for two years as a pathologist in the US Public Health Service, stationed at the Centers for Disease Control in Atlanta, Georgia. In subsequent years he served on the faculty of the Brown University Medical School and then the University of Vermont College of Medicine. It was at Vermont that he began working on Alzheimer’s disease and other age-related neurodegenerative disorders. In 1986, Dr. Perl joined the Mount Sinai School of Medicine in New York, where for 24 years he served as director of the Neuropathology Division and was professor of pathology, psychiatry, and neurosciences.
Professor Perl has authored more than 270 peer-reviewed publications and book chapters and is co-author, with Professor Margaret Esiri, of the 3rd edition of Oppenheimer’s Diagnostic Neuropathology, one of the leading textbooks in his field. He is highly regarded for his work on various aspects of the neuropathology of age-related neurodegenerative disorders, especially the role of environmental factors in their induction. Prior to coming to Uniformed Services University of the Health Sciences, his research had been continually funded by the National Institutes of Health for 32 years. He is the leading authority on the pathology of the fascinating complex of neurodegenerative disorders occurring among the native population living on Guam. He most recently became involved in investigations on the long-term effects of repeated head trauma in former NFL players and other athletes in collaboration with the Boston University Center for the Study of Traumatic Encephalopathy. Professor Perl has won numerous awards for his research as well as his role as a medical educator.
In September 2010, Professor Perl left Mount Sinai to join the faculty of the Uniformed Services University of the Health Sciences in Bethesda, MD. In conjunction with the congressionally mandated Center for Neuroscience and Regenerative Medicine, he has established a state-of-the-art neuropathology laboratory dedicated to research on the acute and long-term effects of traumatic brain injury and PTSD among military personnel.